Skeletal muscle laminopathies are rare genetic disorders caused by pathogenic mutations in the LMNA gene, leading to progressive muscle weakness and other severe symptoms. This study by researchers at UCL demonstrates the use of iPSCs carrying LMNA mutations to model these conditions, offering valuable insights into disease mechanisms and therapeutic opportunities.
We’re pleased to share that CureCMD have now made the iPSC lines featured in this research available through EBiSC. These lines provide an essential tool for researchers studying laminopathies and advancing treatments for these challenging disorders.
Access the collection and learn more here. Let’s drive innovation in skeletal muscle disease research!
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