We’re pleased to announce that KAC Co., Ltd. is now the official partner supporting the promotion and delivery of EBiSC iPSC lines in Japan.
KAC brings extensive experience supplying cell lines, primary cells, culture media, sera and research reagents to laboratories across Japan. Through this collaboration, researchers will benefit from simplified local access, improved logistics and dedicated support when ordering from the EBiSC catalogue of 1000 high-quality iPSC lines covering more than 45 disease areas.
This partnership strengthens EBiSC’s global network and supports our mission to make well-characterised iPSC resources accessible to researchers worldwide.
🧬 Explore EBiSC’s iPSC collection: www.ebisc.org
📩 Contact KAC: https://lnkd.in/eXZi8XP8
🌐 www.kacnet.co.jp
Tag: Disease modelling
Isogenic LRRK2 iPSC lines now available via EBiSC!
Understanding the molecular drivers of Parkinson’s disease is essential for developing effective treatments and the LRRK2 gene remains one of the most significant contributors to both inherited and sporadic forms of the condition.
To investigate this, researchers led by Dr Sally Cowley at the Oxford Parkinson’s Disease Centre have shared a set of LRRK2 gene-edited iPSC lines, including isogenic knockouts and disease-associated variants. These models were generated from high-quality parental lines originally developed through the StemBANCC collaboration, demonstrating the continued impact of large, multi-partner initiatives in building resources which can be shared and used by all researchers.
These iPSC lines are fully quality-controlled and come with comprehensive metadata, enabling robust and reproducible studies of LRRK2 function, cellular pathology, and therapeutic targets.
🔬 Explore these LRRK2 iPSC lines in the EBiSC catalogue: https://ebisc.org/search?q=&hpscreg-genes=%5B%22LRRK2%22%5D&product-status=%5B%5D&gene-edited=true
Big news for biomedical researchers in Australia and New Zealand!
We’re excited to announce that CellBank Australia is now the official distributor of the EBiSC stem cell collection for Australia and New Zealand — making it easier than ever for researchers across Oceania to access 950+ high-quality iPSC lines covering more than 45 disease areas, including cardiovascular, neurological, and metabolic disorders.
This partnership expands EBiSC’s global reach, ensuring that our validated iPSC lines and pre-differentiated cells are available to support research in disease modelling, drug discovery, and regenerative medicine across the region.
Operated by the Children’s Medical Research Institute (CMRI), CellBank brings 18+ years of expertise in authenticated cell lines and quality control services. The collaboration is further strengthened by CMRI’s Stem Cell and Organoid Facility, advancing 3D organoid models and translational research.
🌐 https://www.cellbankaustralia.com/cell-lines-for-distribution/
Congenital Muscular Dystrophy collection now available via EBiSC.
Skeletal muscle laminopathies are rare genetic disorders caused by pathogenic mutations in the LMNA gene, leading to progressive muscle weakness and other severe symptoms. This study by researchers at UCL demonstrates the use of iPSCs carrying LMNA mutations to model these conditions, offering valuable insights into disease mechanisms and therapeutic opportunities.
We’re pleased to share that CureCMD have now made the iPSC lines featured in this research available through EBiSC. These lines provide an essential tool for researchers studying laminopathies and advancing treatments for these challenging disorders.
Access the collection and learn more here. Let’s drive innovation in skeletal muscle disease research!
https://ebisc.org/search?q=CMDi
#Laminopathies #SkeletalMuscleResearch #iPSC #EBiSC #Genetics #DiseaseModeling #RareDiseases
Focal Segmental Glomerulosclerosis (FSGS) iPSCs and clinical data
We’re happy to share that the iPSC lines from the study “Generation of 20 Human Induced Pluripotent Stem Cell Lines from Patients with Focal Segmental Glomerulosclerosis (FSGS)” are available through EBiSC!
These iPSC lines, derived from patients with FSGS, provide a valuable resource for studying kidney disease mechanisms and testing potential therapies. Detailed clinical data is available upon request for researchers looking to deepen their understanding of FSGS.
Explore the iPSC lines and access data via EBiSC here to drive forward your nephrology research.
#FSGS #iPSC #KidneyResearch #EBiSC #GeneticResearch #DiseaseModeling #Nephrology #RegenerativeMedicine
New publication on EBiSC-NEUR1 neurons!
We’re thrilled to see the paper “Measurements of Neurite Extension and Nucleokinesis in an iPSC-Derived Model System Following Microtubule Perturbation” published, showcasing the power of EBiSC iPSC-derived neurons.
This study highlights how iPSC technology can be used to model and measure key cellular processes like neurite extension and nucleokinesis, offering valuable insights into neurodevelopmental diseases. It’s exciting to see how EBiSC-generated iPSC lines are contributing to cutting-edge research that deepens our understanding of cellular dynamics and disease mechanisms.
https://pubmed.ncbi.nlm.nih.gov/39602292
#iPSC #Neurodegeneration #Neuroscience #EBiSC #DiseaseModeling #StemCellResearch #Neurodevelopment