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Happy 10th Birthday EBiSC!

We are very proud to mark 10 years of the European Bank for induced pluripotent Stem Cells distributing high-quality human induced pluripotent stem cell (iPSC) lines.

Initially established in 2014 with support from the Innovative Health Initiative and EFPIA, EBiSC distributed its first iPSC lines in 2016 and since then has shared iPSC lines to researchers all over the world.

With a catalogue of >1000 iPSC lines, covering >45 diseases as well as isogenic, familial and age-sex matched controls, EBiSC has become a trusted resource for researchers internationally, enabling access to well-characterised, quality-controlled iPSCs that underpin advances across a wealth of topics including tissue and disease modelling, organoids, genomics and feeding into drug discovery and regenerative medicine.

We’d like to share a huge thank you to our project partners, collaborators, depositors and Users whose continued engagement has been instrumental in shaping EBiSC’s success. Special thanks to Culture Collections for their previous role as the EBiSC distribution hub. We also recognise the dedication of our teams in Fraunhofer UK Research Ltd and Fraunhofer Institute for Biomedical Engineering who are responsible for operating EBiSC and whose expertise and commitment ensure the highest standards in cell banking, data management, and distribution. Thank you all!

As we look to the future, EBiSC remains committed to expanding access, enhancing quality, and supporting innovation in stem cell research. If you’d like to work with us, get in touch via Contact@EBiSC.org.

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Driving Parkinson’s research forward: EBiSC highlights advanced iPSC models for awareness month.

At the European Bank for induced pluripotent Stem Cells, we are proud to support researchers by providing access to high-quality iPSC models that enable investigation into Parkinson’s disease biology.

The EBiSC collection includes well-characterised iPSCs across a range of genetic variants, including:

STBCi004-B and STBCi004-B-1 (patient derived LRRK2 variant and an isogenic correction)

STBCi026-A from a healthy background alongside its derivatives STBCi026-A-1 (LRRK2 knockout) and STBCi026-A-3 (R1441C variant)

• And patient-derived lines carrying mutations in GBA, LRRK2, and SNCA, reflecting the genetic diversity observed in Parkinson’s disease

You can view all iPSC lines here and use filters to select for donor age, sex and many other characteristics.

We are grateful to the contributions of all individuals living with Parkinson’s disease for making these vital research tools possible!